研究组组长：梅洁 (jmei@ihb.ac.cn)  

研究组介绍：主要从事名特优鱼类遗传育种研究，以无肌间刺、肉质细嫩的黄颡鱼为主要研究对象，系统开展了鱼类性别决定和重要经济性状两性异形的遗传基础及其生物技术操控研究，建立了集“前沿基础研究、育种共性关键技术研发、高产优质新品种研发”为一体的鱼类遗传育种研究体系，培育了水产新品种黄颡鱼“全雄2号” （水产新品种编号GS-04-001-2023）和杂交黄颡鱼“黄优1号” （水产新品种编号GS-02-001-2018）。得到国家重点研发计划、现代农业产业技术体系、国家自然科学基金等项目的资助。

近几年代表著作、论文:  　　   

专著：  

《湖北名优鱼健康养殖技术体系研究》，科学出版社，第四章“黄颡鱼的性别调控和遗传改良”，梅洁

《Sex Control in Aquaculture》，WILEY Blackwell，Chapter 24,“Sexual Size Dimorphism,Sex Determination,and Sex Control in Yellow Catfish”，Jie Mei,Jian-Fang Gui.

期刊论文： 

Gong G,Xiong Y,Xiao S,Li X,Huang P,Liao Q,Han Q,Lin Q,Dan C,Zhou L,Ren F,Zhou Q,Gui JF*,Mei J*. Origin and chromatin remodelling of young X/Y sex chromosomes in catfish with sexual plasticity. National Science Review,2023,10(2):nwac239.

Ren F,Miao R,Xiao R*,Mei J*. m⁶A reader Igf2bp3 enables germ plasm assembly by m⁶A-dependent regulation of gene expression in zebrafish. Science Bulletin,2021,66(11):1119-1128.

Xiong S,Tian J,Ge S,Li Z,Long Z,Guo W,Huang P,He Y,Xiao T,Gui JF,Mei J*. The microRNA-200 cluster on chromosome 23 is required for oocyte maturation and ovulation in zebrafish. Biology of Reproduction. 2020,103(4):769-778.

Ren F,Lin Q,Gong G,Du X,Dan H,Qin W,Miao R,Xiong Y,Xiao R,Li X,Gui JF,Mei J*. Igf2bp3 maintains maternal RNA stability and ensures early embryo development in zebrafish. Communications Biology,2020,3(1):94.

Xiong Y,Wang S,Gui JF,Mei J*. Artificially induced sex-reversal leads to transition from genetic to temperature-dependent sex determination in fish species. Science China Life Science,2020,63(1):157-159.

Gong G,Dan C,Xiao S,Guo W,Huang P,Xiong Y,Wu J,He Y,Zhang J,Li X,Chen N,Gui JF*, Mei J*. Chromosomal-level assembly of yellow catfish genome using third-generation DNA sequencing and Hi-C analysis. GigaScience,2018,7(11):giy120.

Dan C,Lin Q,Gong G,Yang T,Xiong S,Xiong Y,Huang P,Gui JF*,Mei J*. A novel PDZ domain-containing gene is essential for male sex differentiation and maintenance in yellow catfish (Pelteobagrus fulvidraco). Science Bulletin,2018,63: 1420-1430.

Xiong S,Ma W,Jing J,Zhang J,Dan C,Gui JF*,Mei J*. An miR-200 Cluster on Chromosome 23 Regulates Sperm Motility in Zebrafish. Endocrinology,2018,159(5):1982-1991.

Lin Q,Mei J*,Li Z,Zhang X,Zhou L,Gui JF*. Distinct and Cooperative Roles of amh and dmrt1 in Self-Renewal and Differentiation of Male Germ Cells in Zebrafish. Genetics,2017,207(3):1007-1022.

Mei J,Gui JF*. Genetic basis and biotechnological manipulation of sexual dimorphism and sex determination in fish. Sci China Life Sci,2015,58(2):124-36.