2015年7月至今，中国科学院百人计划A类研究员，中国科学院水生生物研究所，湖北武汉 

2008----2015年，研究助理，生化和分子生物学系，佐治亚大学，美国。师从Scott Dougan/Stephen Dalton教授，主要从事脊椎动物早期胚胎发育以及多能干细胞自我更新和分化的机理研究。

2007----2008年，博士后，马普发育生物学研究所，图宾根，德国。

2004---2007年，讲师, 华中农业大学水产学院，武汉，湖北。

1999---2004年，遗传学博士，武汉大学生命科学学院，师从余其兴/刘思阳教授，武汉，湖北。

1991---1995年，生物学学士，四川大学生物系，成都，四川。

长期从事水产经济动物生殖发育和种质创制研究，在雌雄同体鱼类性逆转分子机制和生殖干细胞移植等方向形成特色：1）揭示了环境因素诱导黄鳝性逆转的分子机制，提出了“温度诱导性逆转”的理论假说；2）利用生殖干细胞移植技术创制鲫等新种质。

1、YM Zhang, TT Luo, and Sun YH (2025). A temperature induced sex reversal mechanism in ricefield eels. Water Security and Biology, 100360, https://www.sciencedirect.com/science/article/pii/S2772735125000034

2、

He Xian, Wang Ziming, Cheng Linxi, Wang Han, Sun Yuhua (2025). An antagonistic role of clock genes and lima1 in kidney regeneration. Communications Biology, https://doi.org/10.1038/s42003-025-07455

3、Wang YX, XY Sun, B Xiong, M Duan and YH Sun (2024). Genetic and Environmental Factors Co-Contributing to Behavioral Abnormalities in adnp/adnp2 Mutant Zebrafish. International Journal of Molecular Sciences, 25: 9469. ijms-3174355.

4、

Tong, B.; Sun, YH (2024). Activation of Young LINE-1 Elements by CRISPRa. Int. J. Mol. Sci. 25, 424. https://doi.org/10.3390/ijms25010424

5、Sun XY, Zhang TZ, Cheng LX, Tong B, Jiang W, Sun YH (2023). POGZ suppresses 2C transcriptional program and retrotransposable elements (*corresponding). Cell Reports. 42: 112867

6、

Cao YQ, Wang YX, Zhao Y, Ping Xie, Chen Jun and Sun Yuhua (2023). Transfer of thezp3agene results in changes in egg adhesiveness and buoyancy in transgenic zebrafish. Zoological Research. 44(2): 259−268

7、Feng G, Sun YH (2022). The Polycomb group gene rnf2 is essential for central and enteric neural system development in zebrafish. Frontiers in Neuroscience. 16: 960149. doi: 10.3389/fnins.2022.960149

8、

Sun XY, Cheng LX, Sun YH (2022). Autism-related protein POGZ regulates ESC and ESC neural induction. Molecular Autism. 13: 24. https://doi.org/10.1186/s13229-022-00502-9

9、Sun XY, Wang YX and Sun YH. (2022), Isolation and characterization of germline stem cells in protogynous hermaphroditic Monopterus albus. International Journal of Molecular Sciences. 23: 5861. https://doi.org/10.3390/ ijms23115861 

10、

imin Jiang, Shuyi Guan, Yunti Zhang, Yuhua Sun& Xulin Jiang (2022). Targeted and fluorescence traceable multifunctional host-guest supramolecular gene delivery platform based on poly(cyclodextrin) and rhodamine conjugated disulfide-containing azobenzene-terminated branched polymer. International Journal of Polymeric Materials and Polymeric Biomaterials. https://doi.org/10.1080/00914037.2022.2029438

11、Peng XX, Zhang YY, Feng G, YH Sun (2021). PRC1 maintains regular cardiac contraction via regulating cardiac sarcomere assembly and cardiac conduction system construction. International Journal of Molecular Sciences, 22: 11368

12、

LinXi Cheng, MingHui Xie, WeiHua Qiao, Yu Song, YanYong Zhang, YingChao Geng, WeiLin Xu, Lin Wang, Zheng Wang, Kai Huang, NianGuo Dong & YH Sun (2021). Generation and characterization of cardiac valve endothelial-like cells from human pluripotent stem cells. Communications Biology, https://doi.org/10.1038/s42003-021-02571-7.  

13、Sun XY, XX Peng, YQ Cao, Y Zhou and YH Sun (2020). ADNP promotes neural differentiation by modulating Wnt/β-catenin signaling. Nature Communications, 11: 1984

14、

Sun XY and Yu,WJ, Li Li,YH Sun (2020). ADNP controls gene expression through local chromatin architecture by association with BRG1 and CHD4. Frontiers in Cell and Developmental Biology, 8: 553 

15、XY Sun, J Chen, YY Zhang, S Dougan and YH Sun (2018). Mga Modulates Bmpr1a Activity by Antagonizing Bs69 in Zebrafish. Frontiers in Cell and Developmental Biology, 6: 126

16、

R Berger, YH Sun, M. Kulik et al. (2016). ST8SIA4-Dependent Polysialylation Is Part of a Developmental Program Required for Germ Layer Formation from Human Pluripotent Stem Cells. Stem Cells, 34:1742

17、Amar Singh, Yuhua Sun, Li Li, Steve Qin, and Steve Dalton (2014). Signaling pathways connect the cell cycle to epigenetics and cell fate determination. Stem Cell Reports . 5: 323.  

18、

Yuhua Sun, Weichia Tseng, Rebecca Ball,and Scott Dougan (2014). Extra-embryonic signals under the control of Mga, Max and Smad4 are required for dorsoventral patterning. Developmental Cell, 28: 322.

19、J Champell, YH Sun, A Singh, S Dalton (2013). Myc/Max control Erk signaling and pluripotency by regulation of dual specificity phosphatases 2 and 7. Genes & Development , 27:725-733.

20、

J Phillips-Cremins, M Sauria, A Sanyal, T Gerasimova, B Lajoie, J Bell, CT Ong, T Hookway, C Guo, YH Sun, M Bland, W Wagstaff, S Dalton, T McDevitt, R Sen, J Dekker, J Taylor, V Corces (2013). Architectural protein subclasses shape 3-D organization of genomes during lineage commitment. Cell, 153: 1281.

21、Amar M. Singh, David Reynoids, Timothy Cliff, Satoshi Ohtsuka, Alexa Mattheyses, Yuhua Sun, Laura Menendez, Michael Kulik and Stephen Dalton (2012). Signaling Network Crosstalk in Human Pluripotent Cells: A Smad2/3-Regulated Switch that Controls the Balance between Self-Renewal and Differentiation. Cell stem cell, 10(3): 312-326.

22、

Sun YH, Wloga D. and Dougan S (2011). Embryological manipulations in zebrafish. Methods Mol. Biol., 770: 139-184

23、YH Sun, R. Tang, DP Li, XZ Zhang, J Fu, P. Xie. (2008). Acute effects of microcystins on the transcription of antioxidant enzyme genes in Crucian Carp. Environmental Toxicol. 2008. 23: 145-152

24、

YH Sun, CX Xie, WM Wang, SY Liu, T. Treer, and MM Chang (2007). The genetic variation and biogeography of catostomid fishes based on mitochondrial and nuleic DNA sequences. Journal of Fish Biology. 70: 291-309