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水生所6月26日创新系列讲座预告(2018-08)
作者: | 2018-06-25 | 浏览量:

  时间:2018年6月26日 星期二 上午10:30

  地点:3号实验楼 2楼学术报告厅

  报告专家:Prof. Susan Golden University of California, San Diego

  报告题目:How Cyanobacteria Tell Time

  专家简介:

  Director, Center for Circadian Biology; HHMI Professor; Chancellor's Associates Chair (III) in Molecular Biology; Member of the Faculty of 1000 Biology, Fellow of the American Academy of Microbiology and Member of the National Academy of Sciences.

  Susan Golden received a Ph.D. (1983) in Genetics from the University of Missouri. After postdoctoral research at the University of Chicago, she joined the faculty of Biology at Texas A&M University (1986), where she was promoted to Distinguished Professor in 2003. She joined the Division of Biological Sciences at UCSD in 2008. In the early 1990s she began a collaborative project with C.H. Johnson (Vanderbilt University) and T. Kondo (Nagoya University) that demonstrated circadian rhythms of gene expression in S. elongatus, which is currently the only model organism for a prokaryotic circadian clock. The molecular basis of timekeeping in S. elongatus is now a major focus of her lab.

  代表性文章:

  1. Rubin, B.E., Huynh, T. N., Welkie, D. G., Diamond, S., Simkovsky, R., Pierce, E. C., Taton, A., Lowe, L. C., Lee, J. J., Rifkin, S. A., Woodward, J. J., and Golden, S.S. (2018) High-throughput interaction screens illuminate the role of c-di-AMP in cyanobacterial nighttime survival. PLoS Genet 14: e1007301.

  2. Rubin, B.E., Wetmore, K. M., Price, M. N., Diamond, S., Shultzaberger, R. K., Lowe, L. C., Curtin, G., Arkin, A. P., Deutschbauer, A., and Golden, S.S. (2015) The essential gene set of a photosynthetic organism. Proc Natl Acad Sci U S A 112: E6634-43.

  3. Cohen, S.E., Erb, M. L., Selimkhanov, J., Dong, G., Hasty, J., Pogliano, J., and Golden, S.S. (2014) Dynamic localization of the cyanobacterial circadian clock proteins. Curr Biol 24: 1836-1844.

  4. Dong, G., Yang, Q., Wang, Q., Kim, Y. I., Wood, T. L., Osteryoung, K. W., van Oudenaarden, A., and Golden, S.S. (2010) Elevated ATPase activity of KaiC applies a circadian checkpoint on cell division in Synechococcus elongatus. Cell 140: 529-539.

  5. Ivleva, N.B., Gao, T., LiWang, A. C., and Golden, S.S. (2006) Quinone sensing by the circadian input kinase of the cyanobacterial circadian clock. Proc Natl Acad Sci U S A 103: 17468-17473.

  6. Kondo, T., Mori, T., Lebedeva, N. V., Aoki, S., Ishiura, M., and Golden, S.S. (1997) Circadian rhythms in rapidly dividing cyanobacteria. Science 275: 224-227.

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