论文
论文标题: Human viruses lurking in the environment activated by excessive use of COVID-19 prevention supplies
作者: Hu, Zhichao; Yang, Lihua; Han, Jian; Liu, Zishu; Zhao, Yuxiang; Jin, Yihao; Sheng, Yaqi; Zhu, Lizhong; Hu, Baolan
出版刊物: ENVIRONMENT INTERNATIONAL
出版日期: MAY
出版年份: 2022
卷/期:
DOI: 10.1016/j.envint.2022.107192
论文摘要: Due to extensive COVID-19 prevention measures, millions of tons of chemicals penetrated into natural envi-ronment. Alterations of human viruses in the environment, the neglected perceiver of environmental fluctua-tions, remain obscure. To decipher the interaction between human viruses and COVID-19 related chemicals, environmental samples were collected on March 2020 from surroundings of designated hospitals and receivers of wastewater treatment plant effluent in Wuhan. The virus community and chemical concentration were respec-tively unveiled in virtue of virome and ultra-high-performance liquid chromatography-tandem mass spectrom-etry. The complex relationship between virus and chemical was ulteriorly elaborated by random forest model. As an indicator, environmental viruses were corroborated to sensitively reflect the ecological disturbance originated from pandemic prevention supplies. Chemicals especially trihalomethanes restrained the virus community di-versity. Confronting this adverse scenario, Human gammaherpesvirus 4 and Orf virus with resistance to tri-halomethanes flourished while replication potential of Macacine alphaherpesvirus 1 ascended under glucocorticoids stress. Consequently, human viruses lurking in the environment were actuated by COVID-19 prevention chemicals, which was a constant burden to public health in this ongoing pandemic. Besides, seg-ments of SARS-CoV-2 RNA were detected near designated hospitals, suggesting environment as a missing link in the transmission route. This research innovatively underlined the human health risk of pandemic prevention supplies from the virus -environment interaction, appealing for monitoring of environmental viruses in long term.
== 实验室与学会 ==
  • == 实验室与学会 ==
  • 水产品种创制与高效养殖全国重点实验室
  • 中国科学院藻类生物学重点实验室
  • 农业部淡水养殖病害防治重点实验室
  • 武汉白暨豚保护基金会
  • 湖北省海洋湖沼学会
  • 中国动物学会原生动物学分会
  • 中国动物学会斑马鱼分会
  • 湖北省暨武汉动物学会
  • 中国水产学会鱼病学专业委员会
  • 中国鱼类学会
== 平台建设 ==
  • == 平台建设 ==
  • “一带一路”海域赤潮数据库
  • 国家水生生物种质资源库
  • 国家斑马鱼资源中心
  • 中国科学院淡水藻种库
  • 中国科学院武汉生命科学大型仪器区域中心
  • 湿地生态系统观测研究野外站联盟
  • 中国科学院水生生物研究所分析测试中心
  • 中国科学院超级计算武汉分中心
  • 水生生物博物馆
== 相关网站推荐 ==
  • == 相关网站推荐 ==
  • 中国科学院
  • 农业农村部
  • 科学技术部
  • 生态环境部
  • 国家自然科学基金委员会
  • 中国科学院武汉分院
  • 湖北省科学技术厅
  • 湖北省生态环境厅
  • 湖北省农业农村厅