时间：2019年9月12日 星期四 上午10：30

　　地点：3号实验楼2楼学术报告厅

　　报告专家：Prof. Peter Julian Nixon, Imperial College of London

　　报告题目：Chlorophyll f synthesis by a modified photosystem II complex

　　专家简介：

　　Dr. Peter Julian Nixon is the professor of biochemistry in department of life sciences, Imperial College of London from 2005. He is also a visiting professor in department of life sciences, Nanyang Technological University from 2016. He earned a B.A. from University of Cambridge in 1984 followed by a Ph.D. from Imperial College London in 1988. Professor Peter Julian Nixon is a member of the Plant Section Committee, the Society of Experimental Biology from 2011 and a member of the Editorial Board of JBC from 2013.The goal of Dr. Peter Julian Nixon’s research is to understand fundamental aspects of natural photosynthesis and to use this knowledge to develop robust cyanobacterial, algal and plant solar biorefineries for producing biofuels and high-value products. Current projects include: (1) developing genetic tools and strains for cyanobacterial and algal synthetic biology (2) understanding the assembly and maintenance of the photosynthetic apparatus (3) enhancing photosynthesis in crop plants, algae and cyanobacteria and (4) the overproduction of high-value products in plants and algae via chloroplast transformation.

　　代表性论文：

　　Kiss é, Knoppová J, Pascual GA, Pilny J, Yu J, Halada P, Nixon PJ, Sobotka R, and Komenda J. (2019) A photosynthesis-specific rubredoxin-like protein is required for the efficient association of the D1 and D2 proteins during the initial steps of photosystem II assembly. Plant Cell in press. https://doi.org/10.1105/tpc.19.00155

　　Sel？o TT, W？odarczyk A, Nixon PJ and Norling B (2019) Growth and selection of the cyanobacterium Synechococcus sp. PCC 7002 using alternative nitrogen and phosphorus sources. Metab. Eng. 54: 255-263. https://doi.org/10.1016/j.ymben.2019.04.013

　　Yu J, Knoppová J, Michoux F, Bialek W, Cota E, Shukla MK, Stra？ková A, Aznar GP, Sobotka R, Komenda J, Murray JW and Nixon PJ (2018) Ycf48 involved in the biogenesis of the oxygen-evolving photosystem II complex is a 7-bladed beta-propeller protein. Proc Natl Acad Sci USA 115: E7824-E7833. https://doi:10.1073/pnas.1800609115

　　Sawa M, Fantuzzi A, Bombelli P, Howe CJ, Hellgardt K and Nixon PJ (2017) Electricity produced by digitally printed cyanobacteria. Nat. Commun. 8: 1327. https://doi.org/10.1038/s41467-017-01084-4

　　Becková M, Yu J, Krynická V, Kozlo A, Shao S, Koník P, Komenda J, Murray JW and Nixon PJ (2017) Structure of Psb29/Thf1 and its association with the FtsH protease complex involved in photosystem II repair in cyanobacteria. Phil. Trans. Roy. Soc. B 372: 20160394. https://doi.org/10.1098/rstb.2016.0394

　　Barretto S, Michoux F, Hellgardt K and Nixon PJ (2017) 'Temporary immersion culture hydrodynamics affect growth, viability and transplastomic protein accumulation during in vitro shoot regeneration of Nicotiana tabacum callus: Implications for transplastomic plant-based bioprocess routes to biopharmaceuticals’ Biochem. Eng. J. 117: 73-81. https://doi.org/10.1016/j.bej.2016.10.007

　　Krynická V, Shao S, Nixon PJ and Komenda J (2015) Accessibility controls selective degradation of photosystem II subunits by FtsH protease. Nature Plants 1:15168. https://doi.org/10.1038/nplants.2015.168

　　Knoppová J, Sobotka R, Yu J, Konik P, Halada P, Nixon PJ and Komenda J (2014) Discovery of a chlorophyll binding protein complex involved in the early steps of photosystem II assembly in Synechocystis. Plant Cell 26: 1200-1212. https://doi.org/10.1105/tpc.114.123919

　　Wobbe L and Nixon PJ (2013) The mTERF protein MOC1 terminates mitochondrial DNA transcription in the unicellular green alga Chlamydomonas reinhardtii. Nucl. Acids Res. 41: 6553-6567. https://doi.org/10.1093/nar/gkt313

　　Burgess SJ, Tredwell G, Molnar A, Bundy JG and Nixon PJ (2012) Artificial microRNA-mediated knockdown of pyruvate formate lyase (PFL1) in Chlamydomonas reinhardtii provides evidence for an active 3-hydroxybutyrate production pathway. J. Biotechnol. 162: 57-66. https://doi.org/10.1016/j.jbiotec.2012.05.010