学术活动

水生所10月11日创新系列讲座预告(2019-13)

  时间:2019年10月11日 星期五 上午10:30 

  地点:3号实验楼2楼报告厅 

  报告专家:Prof. Everett Peter Greenberg Washington University 

  报告题目:Pseudomonas aeruginosa quorum sensing-communication, cooperation and conflict in bacteria 

  专家简介: 

  Dr. Peter Greenberg, 华盛顿大学教授,美国国家科学院院士,美国艺术与科学院、美国科学促进会和美国微生物学会成员。于1977年获得马萨诸塞大学微生物学博士学位,1978年在哈弗大学从事博士后研究。2005年至今担任PNAS 杂志编委,2015年获得Shaw Prize in Life Science and Medicine。 

  Dr. Greenberg 是微生物领域内Quorum-sensing及Biofilm 形成机制相关方面研究的奠基人之一,他开创了微生物研究领域的全新视野。发表文章200多篇,相关成果大量发表于Nature,Science,PNAS等杂志(e.g. 1998, Science 280:295-298; 1999, Science 284:1318-1322; 2000, Nature 407:762-764; 2001 Nature 413:860-864; 2002, Nature. 417:552-555; 2008, Nature 454:595-599; 2008, Science 321:256-259; 2012 Science 338:264-266)。最近的研究主要集中在微生物界的新兴领域“微生物社会生物学(sociomicrobiology)”,其研究内容集中在以下三个方面: 

  I. The biochemistry and molecular biology of environmental sensing and response in bacteria with a particular emphasis on a form of chemical communication between bacteria termed quorum sensing. 

  II. The mechanisms by which bacteria switch from a nomadic existence to a sessile biofilm lifestyle and the mechanisms underlying the ability of biofilm bacteria to survive the action of antibiotics. 

  III. The ways in which clonal populations of bacteria can discriminate themselves from other clonal populations. 

  近期发表论文: 

  1. Feltner, J. B., et al. 2016. LasR variant cystic fibrosis isolates reveal an adaptable quorum-sensing hierarchy in Pseudomonas aeruginosa. MBio 7:e01513-16. 

  2. Kostylev, M., et al. 2019. Evolution of the Pseudomonas aeruginosa quorum-sensing hierarchy. Proc Natl Acad Sci USA 116:7027-7032. 

  3. Chen, R., et al. 2019. Social cheating in a Pseudomonas aeruginosa quorum-sensing variant. Proc Natl Acad Sci USA 116:7021-7026. 

  4. Wellington, S. and E. P. Greenberg. 2019. Quorum sensing signal selectivity and the potential for interspecies cross talk. MBio 10: e00146-19. 

   

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